BDBM534275 WO2022086828, Example 3

SMILES Cc1cc(F)c(cc1C(=O)NCC[C@@H](O)c1ccc(cc1)C(F)(F)F)-c1ccn2nc(N)nc2c1

InChI Key InChIKey=MRYPBXQDXGBARZ-HXUWFJFHSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 534275   

TargetReceptor-interacting serine/threonine-protein kinase 1(Homo sapiens (Human))
Bristol-Myers Squibb

WIPO
LigandPNGBDBM534275(WO2022086828, Example 3)
Affinity DataIC50:  0.600nMAssay Description:A solution was prepared containing 0.2 nM Anti GST-Tb (Cisbio, 61GSTTLB), 90.6 nM probe and 1 nM His-GST-TVMV-hRIPKl (1-324) in FRET Buffer (20 mM HE...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed